Antioxidant property of an ethanol extract of the stem of Opuntia ficus-indica var. saboten

被引：414

作者：

Lee, JC

Kim, HR

Kim, J

Jang, YS ^{[1
]}

机构：

[1] Chonbuk Natl Univ, Div Biol Sci, Chonju 561756, South Korea

[2] Chonbuk Natl Univ, Res Ctr Bioact Mat, Chonju 561756, South Korea

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2002年 / 50卷 / 22期

关键词：

Opuntia ficus-indica var. saboten (OFS); reactive oxygen species; antioxidant activity; phenolics;

D O I：

10.1021/jf020388c

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

An ethanol extract of the stem of Opuntia ficus-indica var. saboten (OFS) was assessed to determine the mechanism(s) of its antioxidant activity. The ethanol extract exhibited a concentration-dependent inhibition of linoleic acid oxidation in a thiocyanate assay system. In addition, the OFS extract showed dose-dependent free-radical scavenging activity, including DPPH radicals, superoxide anions (O-2*), and hydroxyl radicals (*OH), using different assay systems. The OFS ethanol extract was also found to be effective in protecting plasmid DNA against the strand breakage induced by hydroxyl radicals in a Fenton's reaction mixture. Furthermore, the extract showed significant (p < 0.01) dose-dependent protection of mouse splenocytes against glucose oxidase-mediated cytotoxicity. Finally, the OFS extract was characterized as containing a high amount of phenolics (180.3 mg/g), which might be the active compounds responsible for the antioxidant properties of the OFS extract.

引用

页码：6490 / 6496

页数：7

共 47 条

[1] OXYGEN FREE-RADICALS AND PARKINSONS-DISEASE [J].