Cardioprotective effects of vegetables:: Is nitrate the answer?

被引：132

作者：

Lundberg, Jon O. ^{[1
]}

Feelisch, Martin

Bjorne, Hakan

Jansson, Emmelie A.

Weitzberg, Eddie

机构：

[1] Karolinska Inst, Dept Physiol & Pharmacol, S-17177 Stockholm, Sweden

[2] Boston Univ, Sch Med, Dept Med, Boston, MA 02118 USA

来源：

NITRIC OXIDE-BIOLOGY AND CHEMISTRY | 2006年 / 15卷 / 04期

基金：

美国国家卫生研究院;

关键词：

nitric oxide; nitrite; cardiovascular; nitrate reductase; hypertension; gastric cancer;

D O I：

10.1016/j.niox.2006.01.013

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A diet rich in fruits and vegetables is associated with a lower risk of certain forms of cancer and cardiovascular disease, but the mechanisms behind this protection are not completely understood. Recent epidemiological studies suggest a cardioprotective action afforded specifically by green leafy vegetables. We here propose that these beneficial effects are related to the high content of inorganic nitrate, which in concert with symbiotic bacteria in the oral cavity is converted into nitrite, nitric oxide, and secondary reaction products with vasodilating and tissue-protective properties. (c) 2006 Elsevier Inc. All rights reserved.

引用

页码：359 / 362

页数：4

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