Combining T cells and IL-10: A new therapy for Crohn's disease?

被引：16

作者：

Madsen, K ^{[1
]}

机构：

[1] Univ Alberta, Edmonton, AB T6G 2C2, Canada

来源：

GASTROENTEROLOGY | 2002年 / 123卷 / 06期

基金：

加拿大健康研究院;

关键词：

D O I：

10.1053/gast.2002.37289

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

[No abstract available]

引用

页码：2140 / 2144

页数：5

共 40 条

[1] An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation [J].

Asseman, C ;

Mauze, S ;

Leach, MW ;

Coffman, RL ;

Powrie, F .

JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 190 (07) :995-1003

[2] Interleukin 10 gene transfer prevents experimental colitis in rats [J].

Barbara, G ;

Xing, Z ;

Hogaboam, CM ;

Gauldie, J ;

Collins, SM .

GUT, 2000, 46 (03) :344-349

[3] Gene therapy in allergic encephalomyelitis using myelin basic protein-specific T cells engineered to express latent transforming growth factor-β1 [J].

Chen, LZ ;

Hochwald, GM ;

Huang, C ;

Dakin, G ;

Tao, H ;

Cheng, C ;

Simmons, WJ ;

Dranoff, G ;

Thorbecke, GJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (21) :12516-12521

[4] Decreased lamina propria effector cell responsiveness to interleukin-10 in ileal Crohn's disease [J].

Colpaert, S ;

Vanstraelen, K ;

Liu, ZJ ;

Penninckx, F ;

Geboes, K ;

Rutgeerts, P ;

Ceuppens, J .

CLINICAL IMMUNOLOGY, 2002, 102 (01) :68-76

[5]

DAVIDSON NJ, 1996, J EXP MED, V184, P1567

[6] Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease [J].

Fedorak, RN ;

Gangl, A ;

Elson, CO ;

Rutgeerts, P ;

Schreiber, S ;

Wild, G ;

Hanauer, SB ;

Kilian, A ;

Cohard, M ;

LeBeaut, A ;

Feagan, B .

GASTROENTEROLOGY, 2000, 119 (06) :1473-1482

[7] Inflammatory bowel disease: Etiology and pathogenesis [J].

Fiocchi, C .

GASTROENTEROLOGY, 1998, 115 (01) :182-205

[8] 2 TYPES OF MOUSE T-HELPER CELL .4. TH2 CLONES SECRETE A FACTOR THAT INHIBITS CYTOKINE PRODUCTION BY TH1 CLONES [J].

FIORENTINO, DF ;

BOND, MW ;

MOSMANN, TR .

JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 170 (06) :2081-2095

[9]

FNAKAJIMA A, 2001, J CLIN INVEST, V107, P1293

[10] INTERLEUKIN-10, A NOVEL B-CELL STIMULATORY FACTOR - UNRESPONSIVENESS OF X-CHROMOSOME LINKED IMMUNODEFICIENCY-B CELLS [J].

GO, NF ;

CASTLE, BE ;

BARRETT, R ;

KASTELEIN, R ;

DANG, W ;

MOSMANN, TR ;

MOORE, KW ;

HOWARD, M .

JOURNAL OF EXPERIMENTAL MEDICINE, 1990, 172 (06) :1625-1631

← 1 2 3 4 →