MRI of small human stroke shows reversible diffusion changes in subcortical gray matter

被引:14
作者
Doege, CA [1 ]
Kerskens, CM [1 ]
Romero, BI [1 ]
Brunecker, P [1 ]
von Pannwitz, W [1 ]
Junge-Hülsing, J [1 ]
Müller, B [1 ]
Villringer, A [1 ]
机构
[1] Humboldt Univ, Fak Med, Univ Klinikum Charite, Neurol Klin & Poliklin, D-10117 Berlin, Germany
关键词
apparent diffusion coefficient; cerebral ischemia; diffusion; human; magnetic resonance imaging; subcortical gray matter;
D O I
10.1097/00001756-200006260-00043
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Six patients who had suffered small cerebral ischemia affecting subcortical gray matter were examined with diffusion weighted imaging (DWI) and T2-weighted imaging within the first 8 h, during the next 2 days and after 5-16 days. Areas of apparent diffusion coefficient (ADC) decreases were observed acutely and reached the maximum size during the subsequent 2 days. Noticeably, in all subjects, a large portion of the ADC lesion was reversible as judged from the lesion size on final T2 image. The regular reversibility of the ADC decreases in this setting may indicate a hitherto not understood pathophysiological process occurring in small ischemic stroke; NeuroReport 11:2021-2024 (C) 2000 Lippincott Williams & Wilkins.
引用
收藏
页码:2021 / 2024
页数:4
相关论文
共 23 条
  • [1] Enlargement of human cerebral ischemic lesion volumes measured by diffusion-weighted magnetic resonance imaging
    Baird, AE
    Benfield, A
    Schlaug, G
    Siewert, B
    Lovblad, KO
    Edelman, RR
    Warach, S
    [J]. ANNALS OF NEUROLOGY, 1997, 41 (05) : 581 - 589
  • [2] SIMULTANEOUS RECORDING OF EEG, DC-POTENTIAL AND DIFFUSION-WEIGHTED NMR IMAGING DURING POTASSIUM-INDUCED CORTICAL SPREADING DEPRESSION IN RATS
    BUSCH, E
    HOEHNBERLAGE, M
    EIS, M
    GYNGELL, ML
    HOSSMANN, KA
    [J]. NMR IN BIOMEDICINE, 1995, 8 (02) : 59 - 64
  • [3] Reperfusion after thrombolytic therapy of embolic stroke in the rat:: Magnetic resonance and biochemical imaging
    Busch, E
    Krüger, K
    Allegrini, PR
    Kerskens, CM
    Gyngell, ML
    Hoehn-Berlage, M
    Hossmann, KA
    [J]. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1998, 18 (04) : 407 - 418
  • [4] TRANSIENT CELL DEPOLARIZATION AFTER PERMANENT MIDDLE CEREBRAL-ARTERY OCCLUSION - AN OBSERVATION BY DIFFUSION-WEIGHTED MRI AND LOCALIZED H-1-MRS
    GYNGELL, ML
    BACK, T
    HOEHNBERLAGE, M
    KOHNO, K
    HOSSMANN, KA
    [J]. MAGNETIC RESONANCE IN MEDICINE, 1994, 31 (03) : 337 - 341
  • [5] Diffusion MRI in patients with transient ischemic attacks
    Kidwell, CS
    Alger, JR
    Di Salle, F
    Starkman, S
    Villablanca, P
    Bentson, J
    Saver, JL
    [J]. STROKE, 1999, 30 (06) : 1174 - 1180
  • [6] Intra-arterial rtPA treatment of stroke assessed by diffusion- and perfusion-weighted MRI
    Lansberg, MG
    Tong, DC
    Norbash, AM
    Yenari, MA
    Moseley, ME
    [J]. STROKE, 1999, 30 (03) : 678 - 680
  • [7] SPREADING WAVES OF DECREASED DIFFUSION-COEFFICIENT AFTER CORTICAL STIMULATION IN THE RAT-BRAIN
    LATOUR, LL
    HASEGAWA, Y
    FORMATO, JE
    FISHER, M
    SOTAK, CH
    [J]. MAGNETIC RESONANCE IN MEDICINE, 1994, 32 (02) : 189 - 198
  • [8] MR IMAGING OF INTRAVOXEL INCOHERENT MOTIONS - APPLICATION TO DIFFUSION AND PERFUSION IN NEUROLOGIC DISORDERS
    LEBIHAN, D
    BRETON, E
    LALLEMAND, D
    GRENIER, P
    CABANIS, E
    LAVALJEANTET, M
    [J]. RADIOLOGY, 1986, 161 (02) : 401 - 407
  • [9] SEPARATION OF DIFFUSION AND PERFUSION IN INTRAVOXEL INCOHERENT MOTION MR IMAGING
    LEBIHAN, D
    BRETON, E
    LALLEMAND, D
    AUBIN, ML
    VIGNAUD, J
    LAVALJEANTET, M
    [J]. RADIOLOGY, 1988, 168 (02) : 497 - 505
  • [10] Clinical utility of diffusion-weighted magnetic resonance imaging in the assessment of ischemic stroke
    Lutsep, HL
    Albers, GW
    DeCrespigny, A
    Kamat, GN
    Marks, MP
    Moseley, ME
    [J]. ANNALS OF NEUROLOGY, 1997, 41 (05) : 574 - 580