Systemic lupus erythematosus in childhood

被引:126
作者
Klein-Gitelman, M [1 ]
Reiff, A
Silverman, ED
机构
[1] Northwestern Univ, Childrens Mem Hosp, Dept Pediat, Div Immunol Rheumatol, Chicago, IL 60614 USA
[2] Univ So Calif, Childrens Hosp Los Angeles, Dept Pediat, Div Rheumatol, Los Angeles, CA 90089 USA
[3] Univ Toronto, Hosp Sick Children, Div Rheumatol, Toronto, ON M5G 1X8, Canada
[4] Univ Toronto, Hosp Sick Children, Res Inst, Toronto, ON M5G 1X8, Canada
[5] Univ Toronto, Hosp Sick Children, Dept Pediat, Toronto, ON M5G 1X8, Canada
[6] Univ Toronto, Hosp Sick Children, Dept Immunol, Toronto, ON M5G 1X8, Canada
关键词
D O I
10.1016/S0889-857X(02)00015-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Systemic lupus erythematosus is a disease of immune dysregulation that strikes approximately 1 in 2000 individuals. The usual patient is a young woman of child-bearing age; however, this illness affects patients of all ages, ethnic backgrounds, and both sexes. Twenty percent of all cases of lupus are diagnosed during the first two decades of life. Perhaps the most essential point in treating a child with lupus is to be aware and concerned about how to deliver treatment to a patient in the middle of their physical, intellectual, and emotional development.
引用
收藏
页码:561 / +
页数:19
相关论文
共 114 条
[1]  
ABELES M, 1980, J RHEUMATOL, V7, P515
[2]  
Abu-Shakra M, 2000, J RHEUMATOL, V27, P1681
[3]  
AGNELLO V, 1972, J IMMUNOL, V108, P837
[4]  
Amit M, 1999, CLIN EXP RHEUMATOL, V17, P467
[5]   Vaccination and systemic lupus erythematosus: the bidirectional dilemmas [J].
Aron-Maor, A ;
Shoenfeld, Y .
LUPUS, 2001, 10 (03) :237-240
[6]  
AUSTIN AH, 1995, NEPHROL DIAL TRANSPL, V19, P1670
[7]  
Austin HA, 1999, SEMIN NEPHROL, V19, P2
[8]   THERAPY OF LUPUS NEPHRITIS - CONTROLLED TRIAL OF PREDNISONE AND CYTOTOXIC DRUGS [J].
AUSTIN, HA ;
KLIPPEL, JH ;
BALOW, JE ;
LERICHE, NGH ;
STEINBERG, AD ;
PLOTZ, PH ;
DECKER, JL .
NEW ENGLAND JOURNAL OF MEDICINE, 1986, 314 (10) :614-619
[9]  
Baqi N, 1996, J AM SOC NEPHROL, V7, P924
[10]   CLINICAL, SEROLOGIC, AND IMMUNOGENETIC STUDIES IN CHILDHOOD-ONSET SYSTEMIC LUPUS-ERYTHEMATOSUS [J].
BARRON, KS ;
SILVERMAN, ED ;
GONZALES, J ;
REVEILLE, JD .
ARTHRITIS AND RHEUMATISM, 1993, 36 (03) :348-354