Toxoplasma gondii recombinant antigens H4 and H11: Use in ELISAs for detection of toxoplasmosis in swine

被引：12

作者：

Andrews, CD

Dubey, JP

Tenter, AM

Webert, DW

机构：

[1] AGR RES SERV,USDA,INST LIVESTOCK & POULTRY SCI,PARASITE BIOL & EPIDEMIOL LAB,BELTSVILLE,MD 20705

[2] TIERARZTLICHEN HSCH HANNOVER,INST PARASITOL,D-3000 HANNOVER,GERMANY

来源：

VETERINARY PARASITOLOGY | 1997年 / 70卷 / 1-3期

关键词：

diagnosis; protozoa; Toxoplasma gondii; immunoassay; zoonosis; recombinant proteins; ELISA; swine;

D O I：

10.1016/S0304-4017(96)01154-5

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Toxoplasma gondii recombinant antigens H4 and H11 were assessed for their potential for use in ELISA for diagnosis of toxoplasmosis in swine. The antigens were evaluated with sera from young pigs experimentally infected with T. gondii. Results were compared with ELISAs based on a native T. gondii antigen extract. Although recombinant antigen ELISAs showed a sharp rise in response with some sera very early after infection, they were relatively non-reactive with late (chronic) infection sera. (C) 1997 Elsevier Science B.V.

引用

页码：1 / 11

页数：11

共 22 条

[1] DIFFERENTIAL TARGETING OF DENSE GRANULE PROTEINS IN THE PARASITOPHOROUS VACUOLE OF TOXOPLASMA-GONDII [J].