Novel catalytic kinetic resolution of racemic epoxides to allylic alcohols

被引：38

作者：

Gayet, A ^{[1
]}

Bertilsson, S ^{[1
]}

Andersson, PG ^{[1
]}

机构：

[1] Uppsala Univ, Inst Chem, Dept Organ Chem, S-75121 Uppsala, Sweden

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 22期

关键词：

D O I：

10.1021/ol025983e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

graphic The kinetic resolution of racemic epoxides via catalytic enantioselective rearrangement to allylic alcohols was investigated. Using the U-salt of (1S,3R,4R)-3-(pyrrolidinyl)methyl-2-azabicyclo [2.2.1] heptane 1 as catalyst allowed both epoxides and allylic alcohols to be obtained in an enantioenriched form.

引用

页码：3777 / 3779

页数：3

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