A right handed peptide helix containing a central double D-amino acid segment

被引：20

作者：

Aravinda, S

Shamala, N ^{[1
]}

Desiraju, S

Balaram, P

机构：

[1] Indian Inst Sci, Dept Phys, Bangalore 560012, Karnataka, India

[2] Indian Inst Sci, Mol Biophys Unit, Bangalore 560012, Karnataka, India

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 20期

关键词：

D O I：

10.1039/b207960g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The crystal structure of the 13 residue peptide Boc-Leu-Aib-Val-Ala-Leu-Aib-Val-(D)Ala-(D)Leu-Aib-Leu-Aib-Val-OMe reveals a continuous helical conformation providing an unambiguous characterization of contiguous D-residues in a right handed peptide helix.

引用

收藏

页码：2454 / 2455

页数：2

相关论文

共 25 条

[1]

[Anonymous], 2015, Acta Crystallogr., V71, P3

[2] An unusual C-H•••O hydrogen bond mediated reversal of polypeptide chain direction in a synthetic peptide helix [J].

Aravinda, S ;

Shamala, N ;

Pramanik, A ;

Das, C ;

Balaram, P .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 273 (03) :933-936

[3]

Banerjee A, 1996, BIOPOLYMERS, V39, P279, DOI 10.1002/(SICI)1097-0282(199609)39:3<279::AID-BIP1>3.0.CO

[4]

2-L

[5] LINEAR OLIGOPEPTIDES. 81. SOLID-STATE AND SOLUTION CONFORMATION OF HOMOOLIGO(ALPHA-AMINOISOBUTYRIC ACIDS) FROM TRIPEPTIDE TO PENTAPEPTIDE - EVIDENCE FOR A 310 HELIX [J].

BENEDETTI, E ;

BAVOSO, A ;

DIBLASIO, B ;

PAVONE, V ;

PEDONE, C ;

CRISMA, M ;

BONORA, GM ;

TONIOLO, C .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1982, 104 (09) :2437-2444

[6] Determination of stereochemistry stability coefficients of amino acid side-chains in an amphipathic α-helix [J].

Chen, Y ;

Mant, CT ;

Hodges, RS .

JOURNAL OF PEPTIDE RESEARCH, 2002, 59 (01) :18-33

[7]

Dunitz JD, 2001, ANGEW CHEM INT EDIT, V40, P4167, DOI 10.1002/1521-3773(20011119)40:22<4167::AID-ANIE4167>3.0.CO

[8]

2-Q

[9] THE HELIX-FORMING PROPENSITY OF D-ALANINE IN A RIGHT-HANDED ALPHA-HELIX [J].

FAIRMAN, R ;

ANTHONYCAHILL, SJ ;

DEGRADO, WF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (13) :5458-5459

[10] Structure of Z-(Aib)9OBut [J].

Gessmann, R ;

Bruckner, H ;

Kokkinidis, M .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1998, 54 :300-307