Established treatments for acute ischaemic stroke

被引：95

作者：

Khaja, Aslam M. ^{[1
]}

Grotta, James C. ^{[1
]}

机构：

[1] Univ Texas, Dept Neurol, Houston, TX 77030 USA

来源：

LANCET | 2007年 / 369卷 / 9558期

关键词：

D O I：

10.1016/S0140-6736(07)60154-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This article reviews the recommended management of patients presenting to accident and emergency departments with acute ischaemic stroke, and focuses on thrombolysis. The review includes initial management, recommended clinical, laboratory, and radiographic examinations. Appropriate general medical care, consisting of monitoring of oxygenation, fever, blood pressure, and blood glucose concentrations are examined. Criteria for thrombolysis with intravenous recombinant tissue plasminogen activator (rt-PA) are discussed. Complications of rt-PA therapy, such as haemorrhagic transformation and angio-oedema, are reviewed. An approach to management of rt-PA complications is outlined. Only a small percentage of acute ischaemic stroke patients meet criteria for rt-PA; therefore, alternative acute treatment strategies are also discussed. Acute medical and neurological complications in stroke patients are analysed, along with recommendations for treatment.

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收藏

页码：319 / 330

页数：12

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