Implementing intensive control of blood glucose concentration and blood pressure in type 2 diabetes in England: cost analysis (UKPDS 63)

被引:58
作者
Gray, A
Clarke, P
Farmer, A
Holman, R
机构
[1] Univ Oxford, Inst Hlth Sci, Dept Primary Hlth Care, Oxford OX1 2JD, England
[2] Univ Oxford, Nuffield Dept Clin Med, Diabet Trials Unit, Oxford OX2 6HE, England
[3] Univ Oxford, Inst Hlth Sci, Dept Publ Hlth, Hlth Econ Res Ctr, Oxford OX3 7LF, England
来源
BRITISH MEDICAL JOURNAL | 2002年 / 325卷 / 7369期
基金
英国惠康基金;
关键词
D O I
10.1136/bmj.325.7369.860
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective To estimate the incremental cost of implementing policies for more intensive control of blood glucose concentration and blood pressure for all patients with type 2 diabetes in England. Design Extrapolation of resource use and cost data derived from a randomised controlled trial. Setting General practice, outpatient care, and inpatient care. Population Trial population with diagnosed type 2 diabetes in England extrapolated to the population of England. Main outcome measures Total costs based on use of healthcare resources including costs of management, treatment, and hospitalisation. Results The incremental net annual cost of implementing more intensive control of blood glucose and blood pressure to all people with diagnosed type 2 diabetes in England is estimated to be pound100.5m ($156m; is not an element of159m), which is equivalent to less than 1% of the proposed additional annual expenditure on the NHS in 2001-5. This estimate varied in sensitivity analyses from pound67m to pound121m. Conclusions Policies to improve control of blood glucose and blood pressure of people with type 2 diabetes are effective in reducing complications associated with the disease and are also cost effective. The total cost represents a small fraction of the NHS's spending plans.
引用
收藏
页码:860 / 863
页数:8
相关论文
共 53 条
[1]   DECISION LATITUDE, PSYCHOLOGIC DEMAND, JOB STRAIN, AND CORONARY HEART-DISEASE IN THE WESTERN ELECTRIC STUDY [J].
ALTERMAN, T ;
SHEKELLE, RB ;
VERNON, SW ;
BURAU, KD .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1994, 139 (06) :620-627
[2]  
*AUD COMM, 2000, TEST TIM REV DIAB SE
[3]  
BLACK DAK, 1975, BRIT J PREV SOC MED, V29, P222
[4]   Two alternative job stress models and the risk of coronary heart disease [J].
Bosma, H ;
Peter, R ;
Siegrist, J ;
Marmot, M .
AMERICAN JOURNAL OF PUBLIC HEALTH, 1998, 88 (01) :68-74
[5]  
*BRIT MED ASS ROYA, 1999, BRIT NAT FORM
[6]   Association between psychosocial work characteristics and health functioning in American women: prospective study [J].
Cheng, YW ;
Kawachi, I ;
Coakley, EH ;
Schwartz, J ;
Colditz, G .
BMJ-BRITISH MEDICAL JOURNAL, 2000, 320 (7247) :1432-1436
[7]   Cost-effectiveness analysis of intensive blood-glucose control with metformin in overweight patients with Type II diabetes (UKPDS No. 51) [J].
Clarke, P ;
Gray, A ;
Adler, A ;
Stevens, R ;
Raikou, M ;
Cull, C ;
Stratton, I ;
Holman, R .
DIABETOLOGIA, 2001, 44 (03) :298-304
[8]  
Claxton K, 1996, HEALTH ECON, V5, P513, DOI 10.1002/(SICI)1099-1050(199611)5:6<513::AID-HEC237>3.0.CO
[9]  
2-9
[10]   Guidelines for authors and peer reviewers of economic submissions to the BMJ [J].
Drummond, MF ;
Jefferson, TO .
BRITISH MEDICAL JOURNAL, 1996, 313 (7052) :275-283