Evolution of transcription-regulating proteins: caveat lector!

被引：1

作者：

Arst, HN ^{[1
]}

Holden, DW ^{[1
]}

Caddick, MX ^{[1
]}

机构：

[1] UNIV LIVERPOOL,SCH BIOL SCI,LIVERPOOL L69 7ZD,MERSEYSIDE,ENGLAND

来源：

GENE | 1997年 / 173卷

关键词：

areA; Aspergillus nidulans; dotplot; Neurospora crassa; nit-2; nitrogen metabolite repression; sequence alignments;

D O I：

10.1016/S0378-1119(97)90018-4

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The paper of Hawkins et al. [Gene 146 (1994) 145-158] reports incorrect descriptions of mutant phenotypes, omits mention of the absence of a highly relevant glutamine-binding site and contains sequence alignments which might mislead the reader. Extensive sequence analysis reveals as untenable a central hypothesis of the paper concerning a possible evolutionary relationship between anthranilate synthetases and the transcription factors mediating nitrogen metabolite repression in fungi.

引用

页码：S1 / S4

页数：4

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