Is intestinal metaplasia of the stomach reversible?

被引:42
作者
Walker, MM [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Fac Med, Dept Histopathol, London W2 1PG, England
关键词
D O I
10.1136/gut.52.1.1
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Intestinal metaplasia (IM) of the stomach is a risk factor in developing intestinal-type gastric cancer and hence the question of reversibility is vital. There is emerging epidemiological evidence that with long term follow up, IM may be reversible although a combination of antioxidant agents and eradication of H pylori may be necessary to achieve this. The pathogenesis of IM is currently being elucidated and it is likely that a combination of bacterial, host, and environmental factors will be shown to lead to IM. In assessing gastric cancer risk, histochemical typing of IM will most probably be replaced by molecular markers.
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页码:1 / 4
页数:4
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