SNF1/AMPK/SnRK1 kinases, global regulators at the heart of energy control?

被引：297

作者：

Polge, Cecile

Thomas, Martine ^{[1
]}

机构：

[1] Univ Paris 11, UMR CNRS 8618, Inst Biotechnol Plantes, Lab Signalisat & Regulat Coordonee Metab Carbone, F-91405 Orsay, France

[2] Univ Grenoble 1, CEA, UMR5168, Physiol Cellulaire Vegetale Lab, F-38054 Grenoble, France

来源：

TRENDS IN PLANT SCIENCE | 2007年 / 12卷 / 01期

关键词：

D O I：

10.1016/j.tplants.2006.11.005

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The SNF1-related kinases are considered to be crucial elements of transcriptional, metabolic and developmental regulation in response to stress. In yeast, SNF1 is one of the main regulators in the shift from fermentation to aerobic metabolism; AMPK, its mammalian counterpart, is a master metabolic regulator involved in a variety of metabolic disorders such as diabetes and obesity. The aim of this review is to examine the literature concerning SnRK1 proteins, the SNF1 homologues in plants. The remarkable structural similarities between the plant complexes and those of yeast and mammalian suggest the existence of a common ancestral function in the regulation of energy and carbon metabolism. We will also highlight some distinctive features acquired by the plant proteins during evolution.

引用

页码：20 / 28

页数：9

共 83 条

[1] Intrasteric control of AMPK via the γ1 subunit AMP allosteric regulatory site [J].

Adams, J ;

Chen, ZP ;

Van Denderen, BJW ;

Morton, CJ ;

Parker, MW ;

Witters, LA ;

Stapleton, D ;

Kemp, BE .

PROTEIN SCIENCE, 2004, 13 (01) :155-165

[2] COMPLEMENTATION OF SNF1, A MUTATION AFFECTING GLOBAL REGULATION OF CARBON METABOLISM IN YEAST, BY A PLANT PROTEIN-KINASE CDNA [J].

ALDERSON, A ;

SABELLI, PA ;

DICKINSON, JR ;

COLE, D ;

RICHARDSON, M ;

KREIS, M ;

SHEWRY, PR ;

HALFORD, NG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (19) :8602-8605

[3] AMP-activated protein kinase plays a role in the control of food intake [J].

Andersson, U ;

Filipsson, K ;

Abbott, CR ;

Woods, A ;

Smith, K ;

Bloom, SR ;

Carling, D ;

Small, CJ .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (13) :12005-12008

[4] Arabidopsis thaliana proteins related to the yeast SIP and SNF4 interact with AKINα1, an SNF1-like protein kinase [J].

Bouly, JP ;

Gissot, L ;

Lessard, P ;

Kreis, M ;

Thomas, M .

PLANT JOURNAL, 1999, 18 (05) :541-550

[5]

CARLSON M, 1981, GENETICS, V98, P25

[6] MUTATIONAL ANALYSIS OF THE SACCHAROMYCES-CEREVISIAE SNF1 PROTEIN-KINASE AND EVIDENCE FOR FUNCTIONAL INTERACTION WITH THE SNF4 PROTEIN [J].

CELENZA, JL ;

CARLSON, M .

MOLECULAR AND CELLULAR BIOLOGY, 1989, 9 (11) :5034-5044

[7] SIMILAR SUBSTRATE RECOGNITION MOTIFS FOR MAMMALIAN AMP-ACTIVATED PROTEIN-KINASE, HIGHER-PLANT HMG-COA REDUCTASE KINASE-A, YEAST SNF1, AND MAMMALIAN CALMODULIN-DEPENDENT PROTEIN-KINASE-I [J].

DALE, S ;

WILSON, WA ;

EDELMAN, AM ;

HARDIE, DG .

FEBS LETTERS, 1995, 361 (2-3) :191-195

[8] BACTERIAL EXPRESSION OF THE CATALYTIC DOMAIN OF 3-HYDROXY-3-METHYLGLUTARYL-COA REDUCTASE (ISOFORM HMGR1) FROM ARABIDOPSIS-THALIANA, AND ITS INACTIVATION BY PHOSPHORYLATION AT SER577 BY BRASSICA-OLERACEA 3-HYDROXY-3-METHYLGLUTARYL-COA REDUCTASE KINASE [J].

DALE, S ;

ARRO, M ;

BECERRA, B ;

MORRICE, NG ;

BORONAT, A ;

HARDIE, DG ;

FERRER, A .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1995, 233 (02) :506-513

[9] PURIFICATION OF THE AMP-ACTIVATED PROTEIN-KINASE ON ATP-GAMMA-SEPHAROSE AND ANALYSIS OF ITS SUBUNIT STRUCTURE [J].

DAVIES, SP ;

HAWLEY, SA ;

WOODS, A ;

CARLING, D ;

HAYSTEAD, TAJ ;

HARDIE, DG .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1994, 223 (02) :351-357

[10] PATHOGENESIS OF NIDDM - A BALANCED OVERVIEW [J].

DEFRONZO, RA ;

BONADONNA, RC ;

FERRANNINI, E .

DIABETES CARE, 1992, 15 (03) :318-368

← 1 2 3 4 5 6 7 8 9 →