MMDB: Entrez's 3D-structure database

被引:119
作者
Chen, J [1 ]
Anderson, JB [1 ]
DeWeese-Scott, C [1 ]
Fedorova, ND [1 ]
Geer, LY [1 ]
He, SQ [1 ]
Hurwitz, DI [1 ]
Jackson, JD [1 ]
Jacobs, AR [1 ]
Lanczycki, CJ [1 ]
Liebert, CA [1 ]
Liu, CL [1 ]
Madej, T [1 ]
Marchler-Bauer, A [1 ]
Marchler, GH [1 ]
Mazumder, R [1 ]
Nikolskaya, AN [1 ]
Rao, BS [1 ]
Panchenko, AR [1 ]
Shoemaker, BA [1 ]
Simonyan, V [1 ]
Song, JS [1 ]
Thiessen, PA [1 ]
Vasudevan, S [1 ]
Wang, YL [1 ]
Yamashita, RA [1 ]
Yin, JJ [1 ]
Bryant, SH [1 ]
机构
[1] Natl Lib Med, Natl Ctr Biotechnol Informat, NIH, Bethesda, MD 20894 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1093/nar/gkg086
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
dimensional structures are now known within most protein families and it is likely, when searching a sequence database, that one will identify a homolog of known structure. The goal of Entrez' s 3D- structure database is to make structure information and the functional annotation it can provide easily accessible to molecular biologists. To this end, Entrez' s search engine provides several powerful features: ( i) links between databases, for example between a protein s sequence and structure; ( ii) precomputed sequence and structure neighbors; and ( iii) structure and sequence/ structure alignment visualization. Here, we focus on a new feature of Entrez' s Molecular Modeling Database ( MMDB) : Graphical summaries of the biological annotation available for each 3D structure, based on the results of automated comparative analysis. MMDB is available at: http: / / www. ncbi. nlm. nih. gov/ Entrez/ structure. html.
引用
收藏
页码:474 / 477
页数:4
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