Clostridium difficile-associated diarrhea after living donor liver transplantation

被引:19
作者
Hashimoto, Masao [1 ]
Sugawara, Yasuhiko [1 ]
Tamura, Surnihito [1 ]
Kaneko, Junichi [1 ]
Matsui, Yuichi [1 ]
Togashi, Junichi [1 ]
Makuuchi, Masatoshi [1 ]
机构
[1] Univ Tokyo, Grad Sch Med, Dept Surg, Artificial Organ & Transplantat Div,Bunkyo Ku, Tokyo 1138655, Japan
关键词
living donor liver transplantation; Clostridium difficile; diarrhea;
D O I
10.3748/wjg.v13.i14.2072
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
AIM: To assess the incidence and analyze the risk factors for Clostridium difficile-associated diarrhea (CDAD) after living donor liver transplantation (LDLT) in adult. METHODS: The micobiological data and medical records of 242 adult recipients that underwent LDLT at the Tokyo University Hospital were analyzed retrospectively. The independent risk factors for postoperative CDAD were identified. RESULTS: Postoperative CDAD occurred in 11 (5%) patients. Median onset of CDAD was postoperative d 19 (range, 5-54). In the multivariate analyses, male gender (odds ratio, 4.56) and serum creatinine (>= 1.5 mg/dL, odds ratio, 16.0) independently predicted postoperative CDAD. CONCLUSION: CDAD should be considered in the differential diagnosis of patients with postoperative diarrhea after LDLT. (c) 2007 The WJG Press. All rights reserved.
引用
收藏
页码:2072 / 2076
页数:5
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