Kidney function assessment in the critically ill child: is it time to leave creatinine behind?

被引：14

作者：

Goldstein, Stuart L. ^{[1
]}

机构：

[1] Texas Childrens Hosp, Houston, TX 77030 USA

来源：

CRITICAL CARE | 2007年 / 11卷 / 03期

关键词：

D O I：

10.1186/cc5935

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The accurate diagnosis of acute kidney injury ( AKI) is especially problematic in critically ill patients in whom renal function is in an unsteady state, rendering creatinine-based baseline assessment measures of renal function potentially inadequate. Herrero-Morin and colleagues performed a cross-sectional analysis of the ability of cystatin C and beta(2) microglobulin to reflect creatinine clearance in pediatric patients with AKI. The aim of this commentary is to review the current state of AKI clinical and translational research in the light of the results presented in that study.

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