Amisulpride versus fluoxetine in dysthymia: Preliminary results of a double-blind comparative study

被引：8

作者：

Smeraldi, E

Haefele, E

Crespi, G

Casadei, GL

Biondi, F

Vigorelli, E

机构：

[1] Ospedale San Raffaele, 20127 Milan

[2] Medical Department, Synthélabo, Limito

来源：

EUROPEAN PSYCHIATRY | 1996年 / 11卷

关键词：

amisulpride; benzamide; treatment; dysthymia; fluoxetine;

D O I：

10.1016/0924-9338(96)85189-3

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The efficacy and safety of low doses of amisulpride (50 mg/day) and of fluoxetine (20 mg/day) were compared respectively in 139 and 129 outpatients with dysthymia during three months in a multi-centre double-blind trial. No statistically significant difference between the two groups was found in the number of responders at study-end with the Montgomery and Asberg Depressive Rating Scale, which was the main criterion for efficacy. In addition, amisulpride was well tolerated. These preliminary results suggest that low doses of amisulpride may be effective in the treatment of dysthymic patients.

引用

页码：S141 / S143

页数：3

共 12 条

[1]

AGNOLI A, 1989, 37 C SIP ROM 6 11 S2

[2]

BOYER P, 1992, CLIN NEUROPHARMACOL, V15, P23

[3] BEHAVIORAL DEFICITS INDUCED BY LOW-DOSES OF APOMORPHINE IN RATS - EVIDENCE FOR A MOTIVATIONAL AND COGNITIVE DYSFUNCTION WHICH DISCRIMINATES AMONG NEUROLEPTIC DRUGS [J].