Site-specific multivalent carbohydrate labeling of quantum dots and magnetic beads

被引：83

作者：

Sun, XL ^{[1
]}

Cui, WX

Haller, C

Chaikof, EL

机构：

[1] Emory Univ, Sch Med, Dept Surg, Atlanta, GA 30322 USA

[2] Emory Univ, Sch Med, Dept Biomed Engn, Atlanta, GA 30322 USA

[3] Emory Univ, Sch Med, Dept Surg & Biomed Engn, Atlanta, GA 30322 USA

来源：

CHEMBIOCHEM | 2004年 / 5卷 / 11期

关键词：

biocapture; biopolymers; lectin; magnetic beads; quantum dots;

D O I：

10.1002/cbic.200400137

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Glyco-imaging/biocapture. Glycopolymer-based multivalent carbohydrates facilitate high binding affinity and specificity of carbohydrate-protein interactions. Herein, we report site-specific multivalent carbohydrate labeling of quantum-dot and magnetic-bead surfaces using a biotin chain-end- functionalized glycopolymer and demonstrate the potential value of these multivalent carbohydrates in both imaging and biocapture applications.

引用

页码：1593 / 1596

页数：4

共 48 条

[1] Nanocrystal targeting in vivo [J].