The synthesis of mono- and bicyclic ethers via acid catalysed ring-opening cyclisation of tetrahydropyranyl ether derivatives

被引：10

作者：

Dixon, DJ ^{[1
]}

Ley, SV ^{[1
]}

Tate, EW ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2000年 / 12期

关键词：

D O I：

10.1039/a909302h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A range of monocyclic and bicyclic alkenols were synthesised via acid catalysed ring-opening cyclisation of homoallylic tetrahydropyranyl ether derivatives in excellent yield. Upon palladium catalysed hydrogenation these products were reduced with excellent diastereoselectivity to the corresponding saturated cyclic alcohols in essentially quantitative yield.

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收藏

页码：1829 / 1836

页数：8

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