Peptidoglycan detection by mammals and flies

被引:58
作者
Chaput, Catherine
Boneca, Ivo G.
机构
[1] Max Planck Inst, Dept Cellular Microbiol, D-10117 Berlin, Germany
[2] Inst Pasteur, Unite Pathogene Bacterienne Muqueuses, F-75724 Paris 15, France
关键词
peptidoglycan; peptidoglycan recognition proteins; Nod; innate immunity; REQUIREMENTS ALLOWING DETECTION; RECOGNITION PROTEIN-L; NF-KAPPA-B; CRITICAL RESIDUES; IMMUNE-RESPONSE; PGRP-LC; NOD1; TOLL; ACTIVATION; BACTERIA;
D O I
10.1016/j.micinf.2007.01.022
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Peptidoglycan is an essential component of bacteria. The host exploits the peptidoglycan particular composition and uniqueness to bacteria for specific bacterial recognition. Insects and mammals accomplish this via receptors such as PGRP and Nod proteins. (c) 2007 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:637 / 647
页数:11
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