Enantioselective organocatalytic intramolecular ring-closing Friedel-Crafts-type alkylation of indoles

被引：115

作者：

Li, Chang-Feng ^{[1
]}

Liu, Hiu ^{[1
]}

Liao, Jie ^{[1
]}

Cao, Yi-Ju ^{[1
]}

Liu, Xiao-Peng ^{[1
]}

Xiao, Wen-Jing ^{[1
]}

机构：

[1] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 10期

关键词：

D O I：

10.1021/ol0703130

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An enantioselective organocatalytic intramolecular ring-closing Friedel-Crafts-type alkylation of indolyl alpha,beta-unsaturated aldehydes has been developed. This powerful new strategy allows enantioselective access to THPIs and THBCs in a straightforward and atom-economical manner.

引用

页码：1847 / 1850

页数：4

共 39 条

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