Applications of multivariate pattern classification analyses in developmental neuroimaging of healthy and clinical populations

被引:54
作者
Bray, Signe [1 ]
Chang, Catie [2 ,3 ]
Hoeft, Fumiko [1 ]
机构
[1] Stanford Univ, Ctr Interdisciplinary Brain Sci Res, Sch Med, Palo Alto, CA 94301 USA
[2] Stanford Univ, Dept Elect Engn, Palo Alto, CA 94301 USA
[3] Stanford Univ, Dept Radiol, Sch Med, Palo Alto, CA 94301 USA
关键词
multivariate pattern classification; development; MRI; fMRI; clinical; INDEPENDENT COMPONENT ANALYSIS; COMMON STEREOTACTIC SPACE; SUPPORT VECTOR MACHINES; VENTRAL TEMPORAL CORTEX; FOCAL CORTICAL ACTIVITY; RESONANCE-IMAGING FMRI; HUMAN VISUAL-CORTEX; FRAGILE-X-SYNDROME; HUMAN BRAIN; SPATIAL-PATTERNS;
D O I
10.3389/neuro.09.032.2009
中图分类号
Q189 [神经科学];
学科分类号
071006 [神经生物学];
摘要
Analyses of functional and structural imaging data typically involve testing hypotheses at each voxel in the brain. However, it is often the case that distributed spatial patterns may be a more appropriate metric for discriminating between conditions or groups. Multivariate pattern analysis has been gaining traction in neuroimaging of adult healthy and clinical populations; studies have shown that information present in neuroimaging data can be used to decode intentions and perceptual states, as well as discriminate between healthy and diseased brains. While few studies to date have applied these methods in pediatric populations, in this review we discuss exciting potential applications for studying both healthy, and aberrant, brain development. We include an overview of methods and discussion of challenges and limitations.
引用
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页数:12
相关论文
共 121 条
[1]
[Anonymous], 1996, COMPUTATIONAL LEARNI
[2]
Voxel-based morphometry - The methods [J].
Ashburner, J ;
Friston, KJ .
NEUROIMAGE, 2000, 11 (06) :805-821
[3]
BANDETTINI PA, 2009, WHATS NEW NEUROIMAGI, P260
[4]
Investigations into resting-state connectivity using independent component analysis [J].
Beckmann, CF ;
DeLuca, M ;
Devlin, JT ;
Smith, SM .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2005, 360 (1457) :1001-1013
[5]
Extensive piano practicing has regionally specific effects on white matter development [J].
Bengtsson, SL ;
Nagy, Z ;
Skare, S ;
Forsman, L ;
Forssberg, H ;
Ullén, F .
NATURE NEUROSCIENCE, 2005, 8 (09) :1148-1150
[6]
BERGSTRAND S, 2009, P 2 INT C BIO SYST S, P273
[7]
Functional imaging of developmental and adaptive changes in neurocognition [J].
Berl, MM ;
Vaidya, CJ ;
Gaillard, WD .
NEUROIMAGE, 2006, 30 (03) :679-691
[8]
Brain development during puberty: state of the science [J].
Blakemore, SJ ;
Choudhury, S .
DEVELOPMENTAL SCIENCE, 2006, 9 (01) :11-14
[9]
Decoding sequential stages of task preparation in the human brain [J].
Bode, Stefan ;
Haynes, John-Dylan .
NEUROIMAGE, 2009, 45 (02) :606-613
[10]
Does human functional brain organization shift from diffuse to focal with development? [J].
Brown, TT ;
Petersen, SE ;
Schlaggar, BL .
DEVELOPMENTAL SCIENCE, 2006, 9 (01) :9-11