An efficient conversion of carboxylic acids into Weinreb amides

被引：49

作者：

Katritzky, AR ^{[1
]}

Yang, HF ^{[1
]}

Zhang, SM ^{[1
]}

Wang, MY ^{[1
]}

机构：

[1] Univ Florida, Dept Chem, Ctr Heterocycl Cpds, Gainesville, FL 32611 USA

来源：

ARKIVOC | 2002年

关键词：

D O I：

10.3998/ark.5550190.0003.b05

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient conversions of carboxylic acids into Weinreb amides were achieved by treatment of N-acylbenzotriazoles 2a-i with NO-dimethylhydroxylamine hydrochloride under mild conditions. No racemization was found when optically active acids were employed.

引用

页码：39 / 44

页数：6

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