Pd-catalyzed selective addition of heteroaromatic C-H bonds to C-C triple bonds under mild conditions

被引：117

作者：

Lu, WJ ^{[1
]}

Jia, CG ^{[1
]}

Kitamura, T ^{[1
]}

Fujiwara, Y ^{[1
]}

机构：

[1] Kyushu Univ, Grad Sch Engn, Dept Chem & Biochem, Fukuoka 812858, Japan

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 19期

关键词：

D O I：

10.1021/ol006156l

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Simple heteroarenes such as pyrroles and indoles undergo addition reactions to C-C triple bonds in the presence of a catalytic amount of Pd(OAc)(2) under very mild conditions, affording cis-heteroarylalkenes in most cases. The cleavage of aromatic CH bonds is the possible rate-determining step in CH2Cl2, and the addition of heteroaromatic C-H bonds to CC triple bonds is in a trans-fashion.

引用

页码：2927 / 2930

页数：4

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