Import of nuclear-encoded proteins into mitochondria

被引：53

作者：

Stojanovski, D ^{[1
]}

Johnston, AJ ^{[1
]}

Streimann, I ^{[1
]}

Hoogenraad, NJ ^{[1
]}

Ryan, MT ^{[1
]}

机构：

[1] La Trobe Univ, Dept Biochem, Melbourne, Vic 3086, Australia

来源：

EXPERIMENTAL PHYSIOLOGY | 2003年 / 88卷 / 01期

关键词：

D O I：

10.1113/eph8802501

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The majority of mitochondrial proteins are encoded by nuclear genes, synthesized in the cytosol and subsequently imported into mitochondria through protein translocation machineries of the outer and inner membranes. In this review, we discuss the arrangement of the various translocation complexes and the function of individual import components. We also outline the various targeting pathways that preproteins can take in order to reach their appropriate sub-mitochondrial compartment.

引用

页码：57 / 64

页数：8