Age-Specific Trends in Incidence of Noncardia Gastric Cancer in US Adults

被引:357
作者
Anderson, William F.
Camargo, M. Constanza [2 ]
Fraumeni, Joseph F., Jr.
Correa, Pelayo [3 ]
Rosenberg, Philip S.
Rabkin, Charles S. [1 ]
机构
[1] NCI, Infect & Immunoepidemiol Branch, Div Canc Epidemiol & Genet, Rockville, MD 20852 USA
[2] Univ Illinois, Div Epidemiol & Biostat, Chicago, IL USA
[3] Vanderbilt Univ, Sch Med, Dept Med, Div Gastroenterol Hepatol & Nutr, Nashville, TN 37212 USA
来源
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2010年 / 303卷 / 17期
基金
美国国家卫生研究院;
关键词
HELICOBACTER-PYLORI INFECTION; UNITED-STATES; TEMPORAL VARIATION; COHORT MODELS; RATES; PERIOD; EPIDEMIOLOGY; ESOPHAGEAL; RISK;
D O I
10.1001/jama.2010.496
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Context For the last 50 years, overall age-standardized incidence rates for noncardia gastric cancer have steadily declined in most populations. However, overall rates are summary measures that may obscure important age-specific trends. Objective To examine effects of age at diagnosis on noncardia gastric cancer incidence trends in the United States. Design, Setting, and Participants Descriptive study with age-period-cohort analysis of cancer registration data from the National Cancer Institute's Surveillance, Epidemiology, and End Results Program, which covers approximately 26% of the US population. From 1977 through 2006, there were 83 225 adults with incident primary gastric cancer, including 39 003 noncardia cases. Main Outcome Measures Overall and age-specific incidence rates, adjusted for period and cohort effects using age-period-cohort models. Results were stratified by race, sex, and socioeconomic status. Results Overall age-standardized annual incidence per 100 000 population declined during the study period from 5.9 (95% confidence interval [CI], 5.7-6.1) to 4.0 (95% CI, 3.9-4.1) in whites, from 13.7 (95% CI, 12.5-14.9) to 9.5 (95% CI, 9.1-10.0) in blacks, and from 17.8 (95% CI, 16.1-19.4) to 11.7 (95% CI, 11.2-12.1) in other races. Age-specific trends among whites varied significantly between older and younger age groups (P < .001 for interaction by age): incidence per 100 000 declined significantly from 19.8 (95% CI, 19.0-20.6) to 12.8 (95% CI, 12.5-13.1) for ages 60 to 84 years and from 2.6 (95% CI, 2.4-2.8) to 2.0 (95% CI, 1.9-2.1) for ages 40 to 59 years but increased significantly from 0.27 (95% CI, 0.19-0.35) to 0.45 (95% CI, 0.39-0.50) for ages 25 to 39 years. Conversely, rates for all age groups declined or were stable among blacks and other races. Age-period-cohort analysis confirmed a significant increase in whites among younger cohorts born since 1952 (P < .001). Conclusions From 1977 through 2006, the incidence rate for noncardia gastric cancer declined among all race and age groups except for whites aged 25 to 39 years, for whom it increased. Additional surveillance and analytical studies are warranted to identify risk factors that may explain this unfavorable trend. JAMA. 2010;303(17):1723-1728 www.jama.com
引用
收藏
页码:1723 / 1728
页数:6
相关论文
共 32 条
[1]   A prospective study of BMI and risk of oesophageal and gastric adenocarcinoma [J].
Abnet, Christian C. ;
Freedman, Neal D. ;
Hollenbeck, Albert R. ;
Fraumeni, Joseph F., Jr. ;
Leitzmann, Michael ;
Schatzkin, Arthur .
EUROPEAN JOURNAL OF CANCER, 2008, 44 (03) :465-471
[2]   Age-Related Crossover in Breast Cancer Incidence Rates Between Black and White Ethnic Groups [J].
Anderson, William F. ;
Rosenberg, Philip S. ;
Menashe, Idan ;
Mitani, Aya ;
Pfeiffer, Ruth M. .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2008, 100 (24) :1804-1814
[3]  
[Anonymous], 2004, IARC MON EV CARC RIS
[4]  
[Anonymous], OR BOOK APPR DRUG PR
[5]   THE COHORT EFFECT AND HELICOBACTER-PYLORI [J].
BANATVALA, N ;
MAYO, K ;
MEGRAUD, F ;
JENNINGS, R ;
DEEKS, JJ ;
FELDMAN, RA .
JOURNAL OF INFECTIOUS DISEASES, 1993, 168 (01) :219-221
[6]   Early-life family structure and microbially induced cancer risk [J].
Blaser, Martin J. ;
Nomura, Abraham ;
Lee, James ;
Stemmerman, Grant N. ;
Perez-Perez, Guillermo I. .
PLOS MEDICINE, 2007, 4 (01) :53-58
[7]   ESSAY What are the consequences of the disappearing human microbiota? [J].
Blaser, Martin J. ;
Falkow, Stanley .
NATURE REVIEWS MICROBIOLOGY, 2009, 7 (12) :887-894
[8]   Early-life family structure and microbially induced cancer risk (vol 4, pg 53, 2007) [J].
Blaser, Martin J. ;
Nomura, Abraham ;
Lee, James ;
Stemmerman, Grant N. ;
Perez-Perez, Guillermo I. .
PLOS MEDICINE, 2007, 4 (02) :397-397
[9]   Secular trends in dietary intake in the United States [J].
Briefel, RR ;
Johnson, CL .
ANNUAL REVIEW OF NUTRITION, 2004, 24 :401-431
[10]   Body mass index and risk of adenocarcinomas of the esophagus and gastric cardia [J].
Chow, WH ;
Blot, WJ ;
Vaughn, TL ;
Risch, HA ;
Gammon, MD ;
Stanford, JL ;
Dubrow, R ;
Schoenberg, JB ;
Mayne, ST ;
Farrow, DC ;
Ahsan, H ;
West, AB ;
Rotterdam, H ;
Niwa, S ;
Fraumeni, JF .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1998, 90 (02) :150-155