Mutant IDH1-specific immunohistochemistry distinguishes diffuse astrocytoma from astrocytosis

被引：82

作者：

Camelo-Piragua, Sandra ^{[2
,4
]}

Jansen, Michael ^{[2
]}

Ganguly, Aniruddha ^{[2
]}

Kim, J. ChulMin ^{[2
]}

Louis, David N. ^{[2
,3
,4
]}

Nutt, Catherine L. ^{[1
,2
,4
]}

机构：

[1] Massachusetts Gen Hosp, Mol Pathol Unit, Charlestown, MA 02129 USA

[2] Massachusetts Gen Hosp, James Homer Wright Pathol Labs, Boston, MA 02114 USA

[3] Massachusetts Gen Hosp, Ctr Canc Res, Boston, MA 02114 USA

[4] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA

来源：

ACTA NEUROPATHOLOGICA | 2010年 / 119卷 / 04期

关键词：

IDH1; MUTATIONS; BRAIN-TUMORS; GLIOMAS; P53;

D O I：

10.1007/s00401-009-0632-y

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：509 / 511

页数：3

共 12 条

[1] Analysis of the IDH1 codon 132 mutation in brain tumors [J].

Balss, Joerg ;

Meyer, Jochen ;

Mueller, Wolf ;

Korshunov, Andrey ;

Hartmann, Christian ;

von Deimling, Andreas .

ACTA NEUROPATHOLOGICA, 2008, 116 (06) :597-602

[2] IDH1 Mutations at Residue p.R132 (IDH1R132) Occur Frequently in High-Grade Gliomas But Not in Other Solid Tumors [J].

Bleeker, Fonnet E. ;

Lamba, Simona ;

Leenstra, Sieger ;

Troost, Dirk ;

Hulsebos, Theo ;

Vandertop, W. Peter ;

Frattini, Milo ;

Molinari, Francesca ;

Knowles, Margaret ;

Cerrato, Aniello ;

Rodolfo, Monica ;

Scarpa, Aldo ;

Felicioni, Lara ;

Buttitta, Fiamma ;

Malatesta, Sara ;

Marchetti, Antonio ;

Bardelli, Alberto .

HUMAN MUTATION, 2009, 30 (01) :7-11

[3]

BRUNER JM, 1991, MODERN PATHOL, V4, P671

[4] Monoclonal antibody specific for IDH1 R132H mutation [J].

Capper, David ;

Zentgraf, Hanswalter ;

Balss, Joerg ;

Hartmann, Christian ;

von Deimling, Andreas .

ACTA NEUROPATHOLOGICA, 2009, 118 (05) :599-601

[5] Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas [J].

Hartmann, Christian ;

Meyer, Jochen ;

Balss, Joerg ;

Capper, David ;

Mueller, Wolf ;

Christians, Arne ;

Felsberg, Joerg ;

Wolter, Marietta ;

Mawrin, Christian ;

Wick, Wolfgang ;

Weller, Michael ;

Herold-Mende, Christel ;

Unterberg, Andreas ;

Jeuken, Judith W. M. ;

Wesseling, Peter ;

Reifenberger, Guido ;

von Deimling, Andreas .

ACTA NEUROPATHOLOGICA, 2009, 118 (04) :469-474

[6] Diagnostic Use of IDH1/2 Mutation Analysis in Routine Clinical Testing of Formalin-Fixed, Paraffin-Embedded Glioma Tissues [J].

Horbinski, Craig ;

Kofler, Julia ;

Kelly, Lindsey M. ;

Murdoch, Geoffrey H. ;

Nikiforova, Marina N. .

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2009, 68 (12) :1319-1325

[7] IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas [J].

Ichimura, Koichi ;

Pearson, Danita M. ;

Kocialkowski, Sylvia ;

Backlund, L. Magnus ;

Chan, Raymond ;

Jones, David T. W. ;

Collins, V. Peter .

NEURO-ONCOLOGY, 2009, 11 (04) :341-347

[8]

LAMMIE GA, 1994, ACTA NEUROPATHOL, V88, P465

[9] THE P53 GENE AND PROTEIN IN HUMAN BRAIN-TUMORS [J].

LOUIS, DN .

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1994, 53 (01) :11-21

[10] An integrated genomic analysis of human glioblastoma Multiforme [J].

Parsons, D. Williams ;

Jones, Sian ;

Zhang, Xiaosong ;

Lin, Jimmy Cheng-Ho ;

Leary, Rebecca J. ;

Angenendt, Philipp ;

Mankoo, Parminder ;

Carter, Hannah ;

Siu, I-Mei ;

Gallia, Gary L. ;

Olivi, Alessandro ;

McLendon, Roger ;

Rasheed, B. Ahmed ;

Keir, Stephen ;

Nikolskaya, Tatiana ;

Nikolsky, Yuri ;

Busam, Dana A. ;

Tekleab, Hanna ;

Diaz, Luis A., Jr. ;

Hartigan, James ;

Smith, Doug R. ;

Strausberg, Robert L. ;

Marie, Suely Kazue Nagahashi ;

Shinjo, Sueli Mieko Oba ;

Yan, Hai ;

Riggins, Gregory J. ;

Bigner, Darell D. ;

Karchin, Rachel ;

Papadopoulos, Nick ;

Parmigiani, Giovanni ;

Vogelstein, Bert ;

Velculescu, Victor E. ;

Kinzler, Kenneth W. .

SCIENCE, 2008, 321 (5897) :1807-1812

← 1 2 →