Lithium perchlorate/diethylether catalyzed aminocyanation of aldehydes

被引：101

作者：

Heydari, A ^{[1
]}

Fatemi, P ^{[1
]}

Alizadeh, AA ^{[1
]}

机构：

[1] Tarbiat Modarres Univ, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 19期

关键词：

D O I：

10.1016/S0040-4039(98)00354-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient one-pot method was developed to give alpha-aminonitriles from aldehydes + amines + TMSCN in LPDE. Optically active alpha-aminonitriles were snythesized by using (S)-(-)- or (R)- (+) alpha-methylbenzylamine, (S)-(-) alpha-methylbenzylamine affords predominantly S-aminonitriles and (R)- (+) alpha-methylbenzylamine leads to the R-aminonitriles. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：3049 / 3050

页数：2

共 20 条

[1]

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[2]

ANH NT, 1977, NOUV J CHIM, V1, P6

[3] CONFORMATIONAL-ANALYSIS OF CHIRAL ALKENES AND OXONIUM IONS - ABINITIO MOLECULAR-ORBITAL CALCULATIONS AND AN IMPROVED MM2 FORCE-FIELD [J].