Bright Three-Photon Luminescence from Gold/Silver Alloyed Nanostructures for Bioimaging with Negligible Photothermal Toxicity

被引：125

作者：

Tong, Ling ^{[2
]}

Cobley, Claire M. ^{[1
]}

Chen, Jingyi ^{[1
]}

Xia, Younan ^{[1
]}

Cheng, Ji-Xin ^{[2
,3
]}

机构：

[1] Washington Univ, Dept Biomed Engn, St Louis, MO 63130 USA

[2] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA

[3] Purdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47907 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 20期

关键词：

biosensors; luminescence; nanostructures; near-infrared imaging; photothermal toxicity; GOLD NANORODS; HIGHLY EFFICIENT; IN-VIVO; 2-PHOTON-INDUCED PHOTOLUMINESCENCE; MULTIPHOTON LUMINESCENCE; OPTICAL-PROPERTIES; CELLULAR UPTAKE; AU NANOCAGES; MICROSCOPY; NANOWIRES;

D O I：

10.1002/anie.201000440

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Equation Present). Au/Ag alloyed nanostructures exhibit a bright three-photon luminescence (3PL; see picture, left) upon excitation by a femtosecond laser at 1290 nm, with an intensity level one order of magnitude higher than pure Au or Ag nanoparticles. As the excitation is outside the range of plasmon resonance, 3PL enables bioimaging (right) with negligible photothermal toxicity. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

收藏

页码：3485 / 3488

页数：4

相关论文

共 44 条

[1] Quantifying the Cellular Uptake of Antibody-Conjugated Au Nanocages by Two-Photon Microscopy and Inductively Coupled Plasma Mass Spectrometry [J].

Au, Leslie ;

Zhang, Qiang ;

Cobley, Claire M. ;

Gidding, Michael ;

Schwartz, Andrea G. ;

Chen, Jingyi ;

Xia, Younan .

ACS NANO, 2010, 4 (01) :35-42

[2] A multimodal platform for nonlinear optical microscopy and microspectroscopy [J].

Chen, Hongtao ;

Wang, Haifeng ;

Slipchenko, Mikhail N. ;

Jung, YooKyung ;

Shi, Yunzhou ;

Zhu, Jiabin ;

Buhman, Kimberly K. ;

Cheng, Ji-Xin .

OPTICS EXPRESS, 2009, 17 (03) :1282-1290

[3] Gold nanocages: Bioconjugation and their potential use as optical imaging contrast agents [J].

Chen, J ;

Saeki, F ;

Wiley, BJ ;

Cang, H ;

Cobb, MJ ;

Li, ZY ;

Au, L ;

Zhang, H ;

Kimmey, MB ;

Li, XD ;

Xia, YN .

NANO LETTERS, 2005, 5 (03) :473-477

[4] Immuno gold nanocages with tailored optical properties for targeted photothermal destruction of cancer cells [J].

Chen, Jingyi ;

Wang, Danling ;

Xi, Jiefeng ;

Au, Leslie ;

Siekkinen, Andy ;

Warsen, Addie ;

Li, Zhi-Yuan ;

Zhang, Hui ;

Xia, Younan ;

Li, Xingde .

NANO LETTERS, 2007, 7 (05) :1318-1322

[5] Highly efficient, wavelength-tunable, gold nanoparticle based optothermal nanoconvertors [J].

Chou, CH ;

Chen, CD ;

Wang, CRC .

JOURNAL OF PHYSICAL CHEMISTRY B, 2005, 109 (22) :11135-11138

[6] Efficient second harmonic generation in ZnO nanorod arrays with broadband ultrashort pulses [J].

Das, Susanta Kumar ;

Bock, Martin ;

O'Neill, Christopher ;

Grunwald, Ruediger ;

Lee, Kyung Moon ;

Lee, Hwang Woon ;

Lee, Soonil ;

Rotermund, Fabian .

APPLIED PHYSICS LETTERS, 2008, 93 (18)

[7] Absolute Two-Photon Absorption Spectra and Two-Photon Brightness of Orange and Red Fluorescent Proteins [J].

Drobizhev, M. ;

Tillo, S. ;

Makarov, N. S. ;

Hughes, T. E. ;

Rebane, A. .

JOURNAL OF PHYSICAL CHEMISTRY B, 2009, 113 (04) :855-859

[8] Two-photon luminescence imaging of cancer cells using molecularly targeted gold nanorods [J].

Durr, Nicholas J. ;

Larson, Timothy ;

Smith, Danielle K. ;

Korgel, Brian A. ;

Sokolov, Konstantin ;

Ben-Yakar, Adela .

NANO LETTERS, 2007, 7 (04) :941-945

[9] Three-photon-induced luminescence of gold nanoparticles embedded in and located on the surface of glassy nanolayers [J].

Eichelbaum, M. ;

Schmidt, B. E. ;

Ibrahim, H. ;

Rademann, K. .

NANOTECHNOLOGY, 2007, 18 (35)

[10] Highly efficient multiphoton-absorption-induced luminescence from gold nanoparticles [J].

Farrer, RA ;

Butterfield, FL ;

Chen, VW ;

Fourkas, JT .

NANO LETTERS, 2005, 5 (06) :1139-1142

← 1 2 3 4 5 →