The first organocatalytic enantioselective inverse-electron-demand hetero-Diels-Alder reaction

被引：260

作者：

Juhl, K ^{[1
]}

Jorgensen, KA ^{[1
]}

机构：

[1] Aarhus Univ, Dept Chem, Danish Natl Res Fdn, Ctr Catalysis, DK-8000 Aarhus C, Denmark

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 13期

关键词：

D O I：

10.1002/anie.200250652

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Catalyzed by chiral amines, aldehydes undergo diastereo- and enantioselective inverse-electron-demand hetero-Diels-Alder reactions with enones (see scheme; PCC = pyridine chlorochromate). The reaction has been optimized with respect to different pyrrolidine catalysts, and tested with various aldehydes and enones.

引用

页码：1498 / 1501

页数：4

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