Collagens: building blocks at the end of the development line

被引：38

作者：

Byers, PH ^{[1
]}

机构：

[1] Univ Washington, Dept Pathol, Seattle, WA 98195 USA

[2] Univ Washington, Dept Med, Seattle, WA 98195 USA

来源：

CLINICAL GENETICS | 2000年 / 58卷 / 04期

关键词：

basement membranes; bone; cartilage; collagen; development; genes; mutations; procollagen;

D O I：

10.1034/j.1399-0004.2000.580404.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Collagens are some of the major building blocks of the vertebrate body. In addition to their structural role, they are important for cell guidance during development and for maintaining tissue integrity. In their absence, phenotypes range from lethal to mild. These studies demonstrate that collaens, in their rich array, play important roles in development and are significant elements in reading the developmental code.

引用

页码：270 / 279

页数：10

共 58 条

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