The JNK signal transduction pathway

被引：870

作者：

Weston, Claire R.

Davis, Roger J. ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Howard Hughes Med Inst, Worcester, MA 01605 USA

[2] Univ Massachusetts, Sch Med, Program Mol Med, Worcester, MA 01605 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2007年 / 19卷 / 02期

关键词：

D O I：

10.1016/j.ceb.2007.02.001

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The c-Jun NH2-terminal kinases (JNKs) are an evolutionarily conserved sub-group of mitogen-activated protein (MAP) kinases. Recent studies have improved our understanding of the physiological function of the JNK pathway. Roles of novel molecules that participate in the JNK pathway have been defined and new insight into the role of JNK in survival signaling, cell death, cancer and diabetes has been achieved.

引用

收藏

页码：142 / 149

页数：8

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