Computational roles for dopamine in behavioural control

被引:640
作者
Montague, PR
Hyman, SE
Cohen, JD
机构
[1] Baylor Coll Med, Div Neurosci, Houston, TX 77030 USA
[2] Baylor Coll Med, Menninger Dept Psychiat & Behav Sci, Houston, TX 77030 USA
[3] Harvard Univ, Cambridge, MA 02138 USA
[4] Princeton Univ, Ctr Study Brain Mind & Behav, Dept Psychol, Princeton, NJ 08544 USA
[5] Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA 15260 USA
关键词
D O I
10.1038/nature03015
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Neuromodulators such as dopamine have a central role in cognitive disorders. In the past decade, biological findings on dopamine function have been infused with concepts taken from computational theories of reinforcement learning. These more abstract approaches have now been applied to describe the biological algorithms at play in our brains when we form value judgements and make choices. The application of such quantitative models has opened up new fields, ripe for attack by young synthesizers and theoreticians.
引用
收藏
页码:760 / 767
页数:8
相关论文
共 72 条
[1]   Beautiful faces have variable reward value: fMRI and behavioral evidence [J].
Aharon, I ;
Etcoff, N ;
Ariely, D ;
Chabris, CF ;
O'Connor, E ;
Breiter, HC .
NEURON, 2001, 32 (03) :537-551
[2]  
[Anonymous], THEORETICAL NEUROSCI
[3]  
[Anonymous], 1988, NEUROPSYCHOLOGY MENT
[4]  
Balleine BW, 2000, J NEUROSCI, V20, P8954
[5]  
BAYER HM, 2002, SOC NEUR ABSTR, V28
[6]   Addiction, dopamine, and the molecular mechanisms of memory [J].
Berke, JD ;
Hyman, SE .
NEURON, 2000, 25 (03) :515-532
[7]   Predictability modulates human brain response to reward [J].
Berns, GS ;
McClure, SM ;
Pagnoni, G ;
Montague, PR .
JOURNAL OF NEUROSCIENCE, 2001, 21 (08) :2793-2798
[8]   What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? [J].
Berridge, KC ;
Robinson, TE .
BRAIN RESEARCH REVIEWS, 1998, 28 (03) :309-369
[9]   Reward learning: Reinforcement, incentives, and expectations [J].
Berridge, KC .
PSYCHOLOGY OF LEARNING AND MOTIVATION: ADVANCES IN RESEARCH AND THEORY, VOL 40, 2001, 40 :223-278
[10]  
Bertsekas D. P., 1996, Neuro Dynamic Programming, V1st