Non-aqueous capillary electrophoresis

被引：169

作者：

Riekkola, ML ^{[1
]}

Jussila, M ^{[1
]}

Porras, SP ^{[1
]}

Valkó, IE ^{[1
]}

机构：

[1] Univ Helsinki, Dept Chem, Analyt Chem Lab, FIN-00014 Helsinki, Finland

来源：

JOURNAL OF CHROMATOGRAPHY A | 2000年 / 892卷 / 1-2期

基金：

芬兰科学院;

关键词：

reviews; nonaqueous capillary electrophoresis; enantiomer separation; detection; electrophoresis; buffer composition;

D O I：

10.1016/S0021-9673(00)00108-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The benefits of non-aqueous capillary electrophoresis have been described in a number of recent publications. The wide selection of organic solvents, with their very different physicochemical properties, broadens our scope to manipulate separation selectivity. The lower currents present in non-aqueous solvents allow the use of high electric field strengths and wide bore capillaries, the latter in turn allowing larger sample load. In many cases detection sensitivity can also be enhanced. The potential of non-aqueous capillary electrophoresis is discussed throughout the paper, and the feasibility of capillary electrophoresis under non-aqueous media is demonstrated with reference to several applications. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：155 / 170

页数：16

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