Genomic analysis of the eukaryotic protein kinase superfamily: a perspective

被引：219

作者：

Hanks, SK ^{[1
]}

机构：

[1] Vanderbilt Univ, Sch Med, Dept Cell & Dev Biol, Nashville, TN 37232 USA

来源：

GENOME BIOLOGY | 2003年 / 4卷 / 05期

关键词：

D O I：

10.1186/gb-2003-4-5-111

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Protein kinases with a conserved catalytic domain make up one of the largest 'superfamilies' of eukaryotic proteins and play many key roles in biology and disease. Efforts to identify and classify all the members of the eukaryotic protein kinase superfamily have recently culminated in the mining of essentially complete human genome data.

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