Detection of gliotoxin in experimental and human aspergillosis

被引：131

作者：

Lewis, RE

Wiederhold, NP

Chi, JD

Han, XY

Komanduri, KV

Kontoyiannis, DP

Prince, RA

机构：

[1] Univ Houston, Coll Pharm, Houston, TX 77030 USA

[2] Univ Texas, MD Anderson Canc Ctr, Houston, TX 77030 USA

来源：

INFECTION AND IMMUNITY | 2005年 / 73卷 / 01期

关键词：

D O I：

10.1128/IAI.73.1.635-637.2005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Gliotoxin was measured in the lungs (mean, 3,976 +/- 1,662 ng/g of tissue) and sera (mean, 36.5 +/- 30.28 ng/ml) of mice with experimentally induced invasive aspergillosis (IA), and levels decreased with antifungal therapy. Gliotoxin could also be detected in the sera of cancer patients with documented (proven or probable) IA.

引用

页码：635 / 637

页数：3

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