World Health Organization experience in the treatment of melanoma

被引：11

作者：

Cascinelli, N

Santinami, M

Maurichi, A

Patuzzo, R

Pennacchioli, E

机构：

[1] Natl Canc Inst, Melanoma & Sarcoma Unit, I-20133 Milan, Italy

[2] WHO, Melanoma Program, Milan, Italy

来源：

SURGICAL CLINICS OF NORTH AMERICA | 2003年 / 83卷 / 02期

关键词：

D O I：

10.1016/S0039-6109(02)00089-0

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

World Health Organization melanoma experience is reported in this article. In more than 30 years of activity this cooperative group found many answers to clinical questions through clinical trials. We discuss: (1) What is adequate surgery of clinically uninvolved regional lymph nodes? (2) What is adequate surgery of the primary tumor? and (3) Is there a role for adjuvant therapy after adequate surgery? In the process, we briefly review all the major clinical trials published by the WHO Melanoma Program.

引用

页码：405 / +

页数：13

共 7 条

[1] Immediate or delayed dissection of regional nodes in patients with melanoma of the trunk: a randomised trial [J].

Cascinelli, N ;

Morabito, A ;

Santinami, M ;

MacKie, RM ;

Belli, F .

LANCET, 1998, 351 (9105) :793-796

[2] Effect of long-term adjuvant therapy with interferon alpha-2a in patients with regional node metastases from cutaneous melanoma: a randomised trial [J].

Cascinelli, N ;

Belli, F ;

MacKie, RM ;

Santinami, M ;

Bufalino, R ;

Morabito, A .

LANCET, 2001, 358 (9285) :866-869

[3]

CASCINELLI N, 1989, CANCER IMMUNOL IMMUN, V28, P282

[4]

SCHRAFFORDTKOOP.H, 1998, J CLIN ONCOL, V16, P2906

[5] INEFFICACY OF IMMEDIATE NODE DISSECTION IN STAGE-1 MELANOMA OF LIMBS [J].

VERONESI, U ;

ADAMUS, J ;

BANDIERA, DC ;

BRENNHOVD, IO ;

CACERES, E ;

CASCINELLI, N ;

CLAUDIO, F ;

IKONOPISOV, RL ;

JAVORSKJ, VV ;

KIROV, S ;

KULAKOWSKI, A ;

LACOUR, J ;

LEJEUNE, F ;

MECHL, Z ;

MORABITO, A ;

RODE, I ;

SERGEEV, S ;

VANSLOOTEN, E ;

SZCZYGIEL, K ;

TRAPEZNIKOV, NN ;

WAGNER, RI .

NEW ENGLAND JOURNAL OF MEDICINE, 1977, 297 (12) :627-630

[6] THIN STAGE-I PRIMARY CUTANEOUS MALIGNANT-MELANOMA - COMPARISON OF EXCISION WITH MARGINS OF 1 OR 3 CM [J].

VERONESI, U ;

CASCINELLI, N ;

ADAMUS, J ;

BALCH, C ;

BANDIERA, D ;

BARCHUK, A ;

BUFALINO, R ;

CRAIG, P ;

DEMARSILLAC, J ;

DURAND, JC ;

VANGEEL, AN ;

HOLMSTROM, H ;

HUNTER, JA ;

JORGENSEN, OG ;

KISS, B ;

KROON, B ;

LACOUR, J ;

LEJEUNE, F ;

MACKIE, R ;

MECHL, Z ;

MITROV, G ;

MORABITO, A ;

NOSEK, H ;

PANIZZON, R ;

PRADE, M ;

SANTI, P ;

VANSLOOTEN, E ;

TOMIN, R ;

TRAPEZNIKOV, N ;

TSANOV, T ;

URIST, M ;

WOZNIAK, KD .

NEW ENGLAND JOURNAL OF MEDICINE, 1988, 318 (18) :1159-1162

[7] A RANDOMIZED TRIAL OF ADJUVANT CHEMOTHERAPY AND IMMUNOTHERAPY IN CUTANEOUS MELANOMA [J].

VERONESI, U ;

ADAMUS, J ;

AUBERT, C ;

BAJETTA, E ;

BERETTA, G ;

BONADONNA, G ;

BUFALINO, R ;

CASCINELLI, N ;

COCCONI, G ;

DURAND, J ;

DEMARSILLAC, J ;

IKONOPISOV, RL ;

KISS, B ;

LEJEUNE, F ;

MACKIE, R ;

MADEJ, G ;

MULDER, H ;

MECHL, Z ;

MILTON, GW ;

MORABITO, A ;

PETER, H ;

PRIARIO, J ;

PAUL, E ;

RUMKE, P ;

SERTOLI, R ;

TOMIN, R .

NEW ENGLAND JOURNAL OF MEDICINE, 1982, 307 (15) :913-916

← 1 →