Reversibility of serum NH3 level in a case of sudden onset and rapidly progressive case of type 2 citrullinemia

被引：10

作者：

Ishikawa, F ^{[1
]}

Nakamuta, M ^{[1
]}

Kato, M ^{[1
]}

Iwamoto, H ^{[1
]}

Enjoji, M ^{[1
]}

Miyata, Y ^{[1
]}

Inoguchi, T ^{[1
]}

Sakai, H ^{[1
]}

Nawata, H ^{[1
]}

机构：

[1] Kyushu Univ, Grad Sch Med Sci, Dept Med & Bioregulatory Sci, Higashi Ku, Fukuoka 8128582, Japan

来源：

INTERNAL MEDICINE | 2000年 / 39卷 / 11期

关键词：

hemodialysis; hemodiafiltration; argininosuccinate synthetase; brain edema; citrin;

D O I：

10.2169/internalmedicine.39.925

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 48-year-old male presented with an acute change in mental status due to a marked elevation of plasma NH, and was diagnosed with citrullinemia with amino acid analysis of blood. Hemodialysis and hemodiafiltration were performed, but serum chemical analysis did not show any improvement which led us to terminate dialysis following intensive care for 3 days. Surprisingly, NH, level had decreased by 6 days after admission, coinciding with normalization of the size of the pupils. Since spontaneous remission had never been discussed, we discuss this relatively rare, but clinically significant entity with regard to its acute phase management and its potential reversibility.

引用

页码：925 / 929

页数：5

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