Diastereoselective Baylis-Hillman reaction: Use of sugar derived aldehydes as chiral electrophiles

被引：32

作者：

Krishna, PR

Kannan, V

Sharma, GVM

Rao, MHVR

机构：

[1] Indian Inst Chem Technol, Discovery Lab, Div Organ Chem 3, Hyderabad 500007, Andhra Pradesh, India

[2] Indian Inst Chem Technol, Ctr Nucl Magnet Resonance, Hyderabad 500007, Andhra Pradesh, India

来源：

SYNLETT | 2003年 / 06期

关键词：

Baylis-Hillman reaction; sugar derived aldehydes; chiral electrophiles; activated alkene; tertiary amine;

D O I：

10.1055/s-2003-38736

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The asymmetric Baylis-Hillman reaction of sugar-derived aldehydes as chiral electrophiles with an activated olefin in dioxane: water (1: 1) with 36-86% de and in good yields is described.

引用

页码：888 / 890

页数：3

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