Suzuki coupling reaction for the solid-phase preparation of 5-substituted nicotinic acid derivatives

被引：20

作者：

Fernàndez, JC

Solé-Feu, L

Fernández-Forner, D

de la Figuera, N

Forns, P

Albericio, F

机构：

[1] Almirall Prodesfarma, Barcelona Sci Pk Unit, Barcelona 08028, Spain

[2] Almirall Prodesfarma, Res Ctr, Barcelona 08024, Spain

[3] Almirall Prodesfarma, Barcelona Biomed Res Inst, Barcelona 08028, Spain

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 04期

关键词：

combinatorial chemistry; Wang resin; Rink resin; Bal resin; 5-bromonicotinic acid; Suzuki coupling; solid-phase organic synthesis;

D O I：

10.1016/j.tetlet.2004.11.153

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The application of the Suzuki coupling reaction to the preparation of small combinatorial libraries using 5-bromonicotinic acid as a scaffold onto three different types of solid support (Wang, Rink, and BAL resin) is described. (C) 2004 Elsevier Ltd. All rights reserved.

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页码：581 / 585

页数：5

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