ASGS: an alternative splicing graph web service

被引:10
作者
Bollina, Durgaprasad
Lee, Bernett T. K.
Tan, Tin Wee
Ranganathan, Shoba [1 ]
机构
[1] Macquarie Univ, Dept Chem & Biomol Sci, Sydney, NSW 2109, Australia
[2] Macquarie Univ, Biotechnol Res Inst, Sydney, NSW 2109, Australia
[3] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Biochem, Singapore 119260, Singapore
关键词
GENOME; DATABASE; GENES;
D O I
10.1093/nar/gkl268
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Alternative transcript diversity manifests itself a prime cause of complexity in higher eukaryotes. The Alternative Splicing Graph Server ( ASGS) is a web service facilitating the systematic study of alternatively spliced genes of higher eukaryotes by generating splicing graphs for the compact visual representation of transcript diversity from a single gene. Taking a set of transcripts in General Feature Format as input, ASGS identifies distinct reference and variable exons, generates a transcript splicing graph, an exon summary, splicing events classification and a single line graph to facilitate experimental analysis. This freely available web service can be accessed at http://asgs.biolinfo.org.
引用
收藏
页码:W444 / W447
页数:4
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