Transformation of triclosan by Trametes versicolor and Pycnoporus cinnabarinus

被引：79

作者：

Hundt, K

Martin, D

Hammer, E

Jonas, U

Kindermann, MK

Schauer, F

机构：

[1] Ernst Moritz Arndt Univ Greifswald, Inst Microbiol & Mol Biol, D-17487 Greifswald, Germany

[2] Ernst Moritz Arndt Univ Greifswald, Inst Chem & Biochem, D-17487 Greifswald, Germany

[3] Sudzucker AG Mannheim, Ochsenfurt, ZAFES, D-67283 Obrigheim, Germany

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2000年 / 66卷 / 09期

关键词：

D O I：

10.1128/AEM.66.9.4157-4160.2000

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We investigated the ability of Trametes versicolor and Pycnoporous cinnabarinus to metabolize triclosan. T. versicolor produced three metabolites, 2-O-(2,4,4'-trichlorodiphenyl ether)-beta-D-xylopyranoside, 2-O-(2,4,4'-trichlorodiphenyl ether)-beta-D-glucopyranoside, and 2,4-dichlorophenol. P. cinnabarinus converted triclosan to 2,2,4'-trichloro-2'-methoxydiphenyl ether and the glucoside conjugate known from T. versicolor. The conjugates showed a distinctly lower cytotoxic and microbicidal activity than triclosan did.

引用

页码：4157 / 4160

页数：4

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