High yield regioselective ring opening of epoxides using samarium chloride hexahydrate

被引：14

作者：

Bhaumik, K ^{[1
]}

Mali, UW ^{[1
]}

Akamanchi, KG ^{[1
]}

机构：

[1] Univ Bombay, Dept Pharmaceut Sci & Technol, Inst Chem Technol, Bombay 400019, Maharashtra, India

来源：

SYNTHETIC COMMUNICATIONS | 2003年 / 33卷 / 09期

关键词：

samarium chloride; azidohydrins; iodohydrins; epoxides;

D O I：

10.1081/SCC-120018790

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Epoxides were converted to the corresponding beta-azidohydrins and beta-iodohydrins using SmCl3.6H(2)O/NaN3 in DMF and SMCl3.6H(2)O/ NaI in acetonitrile respectively. The reactions were highly regioselective, efficient, and gave excellent yields under mild and neutral conditions.

引用

页码：1603 / 1610

页数：8

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