Higher sensitivity of denaturing gradient gel electrophoresis than sequencing in the detection of mutations in DNA from tumor samples

被引：20

作者：

García-Delgado, M ^{[1
]}

González-Navarro, CJ ^{[1
]}

Napal, CC ^{[1
]}

Baldonado, C ^{[1
]}

Vizmanos, JL ^{[1
]}

Gullón, A ^{[1
]}

机构：

[1] Univ Navarra, Fac Sci, Dept Genet, E-31080 Navarra, Spain

来源：

BIOTECHNIQUES | 1998年 / 24卷 / 01期

关键词：

D O I：

10.2144/98241bm15

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

收藏

页码：72 / +

页数：3

相关论文

共 12 条

[1] PROGNOSTIC-SIGNIFICANCE OF TP53 ALTERATIONS IN BREAST-CARCINOMA
ANDERSEN, TI
HOLM, R
NESLAND, JM
HEIMDAL, KR
OTTESTAD, L
BORRESEN, AL
[J]. BRITISH JOURNAL OF CANCER, 1993, 68 (03) : 540 - 548
[2] ALTERATIONS OF THE TP53 GENE AS A POTENTIAL PROGNOSTIC MARKER IN BREAST CARCINOMAS - ADVANTAGES OF USING CONSTANT DENATURANT GEL-ELECTROPHORESIS IN MUTATION DETECTION
ANDERSEN, TI
BORRESEN, AL
[J]. DIAGNOSTIC MOLECULAR PATHOLOGY, 1995, 4 (03) : 203 - 211
[3] BECK JS, 1993, HUM GENET, V91, P25
[4] BORRESEN AL, 1992, CANCER RES, V52, P3234
[5] CONSTANT DENATURANT GEL-ELECTROPHORESIS AS A RAPID SCREENING TECHNIQUE FOR P53 MUTATIONS
BORRESEN, AL
HOVIG, E
SMITHSORENSEN, B
MALKIN, D
LYSTAD, S
ANDERSEN, TI
NESLAND, JM
ISSELBACHER, KJ
FRIEND, SH
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (19) : 8405 - 8409
[6] BOSARI S, 1995, VIRCHOWS ARCH, V427, P229
[7] CARBONE D, 1991, ONCOGENE, V6, P1691
[8] HAMELIN R, 1993, ONCOGENE, V8, P2213
[9] POLYMERASE CHAIN REACTION-BASED METHODS FOR THE DETECTION OF MUTATIONS IN ONCOGENES AND TUMOR-SUPPRESSOR GENES
LODA, M
[J]. HUMAN PATHOLOGY, 1994, 25 (06) : 564 - 571
[10] LYNCH HT, 1981, GENETICS BREAST CANC