Nuclear medicine: from photon's to physiology

被引：8

作者：

Bailey, DL ^{[1
]}

Adamson, KL

机构：

[1] Royal N Shore Hosp, Dept Nucl Med, St Leonards, NSW 2065, Australia

[2] Guys & St Thomas Hosp, London SE1 9RT, England

来源：

CURRENT PHARMACEUTICAL DESIGN | 2003年 / 9卷 / 11期

关键词：

D O I：

10.2174/1381612033455224

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Nuclear Medicine involves studying the time course of radioactive tracers and the physiological response of the body in vivo using external imaging devices. These devices are quantitative and can be used to assay tracer concentrations. This chapter briefly discusses the historical milieu, current state-of-the-art in terms of both single photon and positron tomography (SPECT and PET), and shows a semi-quantitative example of monitoring response to anti-cancer treatment with readily available instrumentation (a gamma camera) and radiopharmaceutical ([F-18]-FDG). Nuclear Medicine is being increasingly utilised in drug discovery and development, and its role looks set to increase even further in the future.

引用

页码：903 / 916

页数：14

共 43 条

[1] SCINTILLATION CAMERA [J].

ANGER, HO .

REVIEW OF SCIENTIFIC INSTRUMENTS, 1958, 29 (01) :27-33

[2]

BAILEY D L, 1989, European Journal of Nuclear Medicine, V15, P452

[3]

Bailey DL, 2000, J NUCL MED, V41, p183P

[4]

BAILEY DL, 1994, EUR J NUCL MED, V21, P381

[5]

BAILEY DL, 1987, J NUCL MED, V28, P844

[6] Transmission scanning in emission tomography [J].

Bailey, DL .

EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1998, 25 (07) :774-787

[7]

BEYER T, 1994, P 1994 IEEE NUCL SCI, V4, P1573

[8] STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT [J].

BLAND, JM ;

ALTMAN, DG .

LANCET, 1986, 1 (8476) :307-310

[9]

Bracewell R. N., 1956, Aust. J. Phys, V9, P198, DOI [10.1071/PH560198, DOI 10.1071/PH560198]

[10] INVERSION OF FAN-BEAM SCANS IN RADIO ASTRONOMY [J].

BRACEWELL, RN ;

RIDDLE, AC .

ASTROPHYSICAL JOURNAL, 1967, 150 (2P1) :427-+

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