Identifying the proteome:: software tools

被引：100

作者：

Fenyö, D ^{[1
]}

机构：

[1] ProteoMetr LLC, New York, NY 10018 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2000年 / 11卷 / 04期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0958-1669(00)00115-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The interest in proteomics has recently increased dramatically and proteomic methods are now applied to many problems in cell biology. The method of choice in proteomics for identifying and characterizing proteins is mass spectrometry combined with database searching. Software tools have been improved to increase the sensitivity of protein identification and methods for evaluating the search results have been incorporated.

引用

收藏

页码：391 / 395

页数：5

相关论文

共 49 条

[1]

Berndt P, 1999, ELECTROPHORESIS, V20, P3521, DOI 10.1002/(SICI)1522-2683(19991201)20:18<3521::AID-ELPS3521>3.0.CO

[2]

2-8

[3] A molecular scanner to automate proteomic research and to display proteome images [J].

Binz, PA ;

Müller, M ;

Walther, D ;

Bienvenut, WV ;

Gras, R ;

Hoogland, C ;

Bouchet, G ;

Gasteiger, E ;

Fabbretti, R ;

Gay, S ;

Palagi, P ;

Wilkins, MR ;

Rouge, V ;

Tonella, L ;

Paesano, S ;

Rossellat, G ;

Karmime, A ;

Bairoch, A ;

Sanchez, JC ;

Appel, RD ;

Hochstrasser, DF .

ANALYTICAL CHEMISTRY, 1999, 71 (21) :4981-4988

[4] RAPID MASS-SPECTROMETRIC PEPTIDE SEQUENCING AND MASS MATCHING FOR CHARACTERIZATION OF HUMAN-MELANOMA PROTEINS ISOLATED BY 2-DIMENSIONAL PAGE [J].

CLAUSER, KR ;

HALL, SC ;

SMITH, DM ;

WEBB, JW ;

ANDREWS, LE ;

TRAN, HM ;

EPSTEIN, LB ;

BURLINGAME, AL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (11) :5072-5076

[5] Role of accurate mass measurement (±10 ppm) in protein identification strategies employing MS or MS MS and database searching [J].

Clauser, KR ;

Baker, P ;

Burlingame, AL .

ANALYTICAL CHEMISTRY, 1999, 71 (14) :2871-2882

[6] Optimization of capillary chromatography ion trap mass spectrometry for identification of gel-separated proteins [J].

Courchesne, PL ;

Jones, MD ;

Robinson, JH ;

Spahr, CS ;

McCracken, S ;

Bentley, DL ;

Luethy, R ;

Patterson, SD .

ELECTROPHORESIS, 1998, 19 (06) :956-967

[7] AN APPROACH TO CORRELATE TANDEM MASS-SPECTRAL DATA OF PEPTIDES WITH AMINO-ACID-SEQUENCES IN A PROTEIN DATABASE [J].

ENG, JK ;

MCCORMACK, AL ;

YATES, JR .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 1994, 5 (11) :976-989

[8] A statistical basis for testing the significance of mass spectrometric protein identification results [J].

Eriksson, J ;

Chait, BT ;

Fenyö, D .

ANALYTICAL CHEMISTRY, 2000, 72 (05) :999-1005

[9] Protein identification using mass spectrometric information [J].

Fenyö, D ;

Qin, J ;

Chait, BT .

ELECTROPHORESIS, 1998, 19 (06) :998-1005

[10] Proteome analysis of Saccharomyces cerevisiae: A methodological outline [J].

Fey, SJ ;

Nawrocki, A ;

Larsen, MR ;

Gorg, A ;

Roepstorff, P ;

Skews, GN ;

Williams, R ;

Larsen, PM .

ELECTROPHORESIS, 1997, 18 (08) :1361-1372

← 1 2 3 4 5 →