Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke

被引：147

作者：

Hill, MD ^{[1
]}

Lye, T ^{[1
]}

Moss, H ^{[1
]}

Barber, PA ^{[1
]}

Demchuk, AM ^{[1
]}

Newcommon, NJ ^{[1
]}

Green, TL ^{[1
]}

Kenney, C ^{[1
]}

Cole-Haskayne, A ^{[1
]}

Buchan, AM ^{[1
]}

机构：

[1] Univ Calgary, Foothills Hosp, Dept Clin Neurosci, Calgary Stroke Program, Calgary, AB T2N 2T9, Canada

来源：

NEUROLOGY | 2003年 / 60卷 / 09期

关键词：

D O I：

10.1212/01.WNL.0000058840.66596.1A

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

One hundred seventy-six consecutive patients treated with IV tissue plasminogen activator (tPA) for acute ischemic stroke were examined prospectively, and orolingual angioedema was found in nine (5.1%; 95% CI 2.3 to 9.5). The reaction was typically mild, transient, and contralateral to the ischemic hemisphere. Risk of angioedema was associated with angiotensin-converting enzyme inhibitors (relative risk [RR] 13.6; 95% CI 3.0 to 62.7) and signs on initial CT of ischemia in the insular and frontal cortex (RR 9.1; 95% CI 1.4 to 30.0).

引用

页码：1525 / 1527

页数：3

共 10 条

[1] Angioedema due to angiotensin-converting enzyme inhibitors
Agostoni, A
Cicardi, M
Cugno, M
Zingale, LC
Gioffré, D
Nussberger, J
[J]. IMMUNOPHARMACOLOGY, 1999, 44 (1-2): : 21 - 25
[2] Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy
Barber, PA
Demchuk, AM
Zhang, JJ
Buchan, AM
[J]. LANCET, 2000, 355 (9216) : 1670 - 1674
[3] The insula and cerebrogenic sudden death
Cheung, RTF
Hachinski, V
[J]. ARCHIVES OF NEUROLOGY, 2000, 57 (12) : 1685 - 1688
[4] Hill MD, 2000, CAN MED ASSOC J, V162, P1281
[5] Hill MD, 2000, CAN MED ASSOC J, V162, P1589
[6] Biochemical basis of angioedema associated with recombinant tissue plasminogen activator treatment - An in vitro experimental approach
Molinaro, G
Gervais, N
Adam, A
[J]. STROKE, 2002, 33 (06) : 1712 - 1716
[7] Left-insular cortex lesions perturb cardiac autonomic tone in humans
Oppenheimer, SM
Kedem, G
Martin, WM
[J]. CLINICAL AUTONOMIC RESEARCH, 1996, 6 (03) : 131 - 140
[8] Asymmetric angioneurotic edema associated with thrombolysis for acute stroke
Pancioli, A
Brott, T
Donaldson, V
Miller, R
[J]. ANNALS OF EMERGENCY MEDICINE, 1997, 30 (02) : 227 - 229
[9] Pexman JHW, 2001, AM J NEURORADIOL, V22, P1534
[10] Evidence of anaphylaxy after alteplase infusion
Rudolf, J
Grond, M
Prince, WS
Schmülling, S
Heiss, WD
[J]. STROKE, 1999, 30 (05) : 1142 - 1143

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