Comparative investigation of the long non-coding M-F genome region of wild-type and vaccine measles viruses

被引：18

作者：

Heider, A

Santibanez, S

Tischer, A

Gerike, E

Tikhonova, N

Ignatyev, G

Mrazova, M

Enders, G

Schreier, E

机构：

[1] Robert Koch Inst, D-13353 Berlin, Germany

[2] Russian Acad Med Sci, Viral Preparat Res Inst, Moscow 109801, Russia

[3] G N Grabrichevsky Moscow Res Inst Epidemiol & Mic, Moscow, Russia

[4] State Sci Ctr Virol & Biotechnol Vector Koltsovo, Res Inst Mol Biol, Novosibirsk, Russia

[5] Natl Inst Publ Hlth, Prague, Czech Republic

[6] Med Lab, Stuttgart, Germany

[7] Inst Virol Infect Dis & Epidemiol, Stuttgart, Germany

来源：

ARCHIVES OF VIROLOGY | 1997年 / 142卷 / 12期

关键词：

D O I：

10.1007/s007050050259

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The sequence of the 300 nucleotides region of the measles virus genome was determined that includes a part of the 3'-untranslated region of the matrix (M) gene, the intergenic region and a part of the 5'-untranslated region of the fusion (F) gene [M-F region] for vaccine strain Leningrad-16 and 14 wild-type isolates. The data obtained demonstrate the variability of this long non-coding M-F region. No mutations in this region of the genome were found which seem to be specific for vaccine strains of measles virus (MV).

引用

页码：2521 / 2528

页数：8

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