One-pot synthesis of new symmetric and asymmetric xanthene dyes

被引：92

作者：

Hilderbrand, Scott A. ^{[1
]}

Weissleder, Ralph ^{[1
]}

机构：

[1] Massachusetts Gen Hosp, Harvard Med Sch, Ctr Mol Imaging Res, Charlestown, MA 02129 USA

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 25期

关键词：

D O I：

10.1016/j.tetlet.2007.04.088

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Symmetric and asymmetric xanthene dyes have been prepared by a convenient one-step procedure from aldehyde and diol or m-aminophenol precursors using concentrated phosphoric acid as a solvent. This protocol provides access to water-soluble dyes with large Stoke's shifts and far-red fluorescence emission. These compounds are envisioned as components of fluorescencebased sensors for a variety of imaging applications. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：4383 / 4385

页数：3

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