Transmission cycles, host range, evolution and emergence of arboviral disease

被引:486
作者
Weaver, SC [1 ]
Barrett, ADT
机构
[1] Univ Texas, Med Branch, Dept Pathol Microbiol & Immunol, Ctr Biodefense & Emerging Infect Dis, Galveston, TX 77555 USA
[2] Univ Texas, Med Branch, Dept Pathol Microbiol & Immunol, Ctr Trop Dis, Galveston, TX 77555 USA
关键词
D O I
10.1038/nrmicro1006
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Many pandemics have been attributed to the ability of some RNA viruses to change their host range to include humans. Here, we review the mechanisms of disease emergence that are related to the host-range specificity of selected mosquito-borne alphaviruses and flaviviruses. We discuss viruses of medical importance, including Venezuelan equine and Japanese encephalitis viruses, dengue viruses and West Nile viruses.
引用
收藏
页码:789 / 801
页数:13
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